Genetic and Biochemical Studies of Partially Active Tryptophan Synthetase Mutants of Saccharomyces cerevisiae
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چکیده
منابع مشابه
Two mechanisms of allelic complementation among tryptophan synthetase mutants of Saccharomyces cerevisiae.
Two different types of allelic complementation were observed in tryptophan synthetase mutants of the yeast Saccharomyces cerevisiae. Each type is associated with a different mechanism for the enzymatic conversion of indole-3-glycerol phosphate (InGP) to tryptophan. Mechanism I is utilized by a hybrid tryptophan synthetase that resembles, but is not identical with, the wild-type enzyme. Mechanis...
متن کاملBiochemical, immunological, and genetic studies with a new type of tryptophan synthetase mutant of Neurospora crassa.
Previous studies have implicated indole-3glycerol phosphate as an intermediate in the biosynthesis of tryptophan in Escherichia coli (Yanofsky, 1956a, b) and Neurospora crassa (Yanofsky and Rachmeler, 1958; DeMoss, Imai, and Bonner, 1958; Suskind and Jordan, 1959). It has also been established that this compound is converted to tryptophan by the enzyme tryptophan synthetase in both organisms (D...
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1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...
Genetic analysis of petite mutants of Saccharomyces cerevisiae: transmissional types.
We have studied a number of petite [rho-] mutants of Saccharomyces cerevisiae induced in a wild-type strain of mitochondrial genotype [ome- CHL(R) ERY(S) OLI(S) (1, 2, 3) PAR(S)] by Berenil and ethidium bromide, all of which have retained two mitochondrial genetic markers, [CHL(R)] and [ERY(S)], but have lost all other known markers. Though stable in their ability to retain these markers in the...
متن کاملSensitivity of tryptophan, tyrosine and phenylalanine mutants of Saccharomyces cerevisiae to phenethyl alcohol.
Phenethyl alcohol inhibits the growth of many microorganisms. It is believed that the growth inhibition is mediated by its effect on the cell membrane. Differences between sensitive and resistant strains are suggested to be due to alterations in membrane structure. We report that, in some strains, an unexpected relationship exists between auxotrophy for tryptophan, tyrosine and phenylalanine an...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1969
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.99.2.590-596.1969